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Urine Test for Kidney Disease

Our kidneys are great excretory organs that can prevent protein from leaking into urine. Therefore, the amount of various proteins in urine can reflect the extent of kidney damage. If you have a urine test, the following substances may be tested.

1. U-TP (urine-total protein)

It used to the total excretion amount of protein in urine and the normal reference value is less than 150 mg/dl. If the test result shows a higher value, it may indicate kidney damage.

2. U-malb (urine-micro albumin)

This test item can reflect the early damage of glomerular filtration membrane mechanical barrier. When the value is above 300 mg/l, you have to consider kidney disease.

3. U-TRF (urine-transferrin)

Compared with U-malb, U-TRF is used to detect the early damage of glomerular filtration membrane charge barrier. U-TRF over 1.9mg/l can be an indicator of this damage.

4. U-IGG (urine-IgG)

If the value of U-IGG is above 8.8 mg/l, it means glomerular filtration membrane has been impaired severely.

5. β2-M (urine β2 microglobulin)

It can be a sign of renal tubular reabsorption function. When its value is over 5.8 mg/l, it may reveal the decline of renal tubular reabsorption function.

6. α1-M (urine α1 microglobulin)

It is more sensitive and stable than β2-M to reflect the damage to renal tubular reabsorption function.

7. α2-M (urine α2-macroglobulin)

It is a sign of post-renal proteinuria.

8. K light chain

It is used to detect pre-renal proteinuria and can also be been in other diseases such as light chain disease, multiple myeloma and lymphoma.

9. λlight chain

Similar with K light chain, it can also detect pre-renal proteinuria and be seen in the above diseases.

10. Urine-NAG

It is an indicator of inflammatory damage to renal tubular epithelial cells.

11. Urine-GGT

Similar with NAG, GGT can also reveal the damage especially immune damage to renal tubular epithelial cells.

12. Urine osmotic pressure

It is one clinical index to assess the concentration and dilution function of distal renal tubules.

From the above test items, you can detect the extent and location of your kidney damage.