Proteinuria May Not Be Serious In Kidney Disease
2019-02-25 14:12
Judging the condition of Kidney Disease, many patients are accustomed to looking at the amount of urinary protein. However, there are several kinds of nephropathy, which may progress from the onset of the disease to uremia. Urinary protein is always very small and can not be used to judge the condition of the disease.
1. Hypertensive nephropathy
Long-term hypertension, the preferred injury is the renal tubule, patients will increase nocturnal urine, urine proportion decreased, serum creatinine increased.
Glomerular damage in hypertensive nephropathy is relatively late, even after renal failure, urinary protein and edema are not obvious. Perhaps the serum creatinine is high, urinary protein is still trace, when serum creatinine is 300 or 400, urinary protein will be more obvious, but generally not more than 1 g.
2. Diabetic nephropathy
In patients with diabetic nephropathy, urinary protein is normal at the onset of renal failure.
After a period of time, albumin increased slightly, and the inconspicuous microalbumin continued until nearly four stages. When urinary protein is significantly elevated and enters the clinical proteinuria stage, renal failure is serious and is close to uremia.
Diabetic nephropathy, as well as hypertensive nephropathy patients, can not see urinary protein negative or weak positive think that the kidney is okay, should be regularly checked for microalbumin, in the early stage of kidney injury to start the prevention and treatment of nephropathy.
3. Polycystic Kidney Disease
Polycystic kidney disease is a hereditary kidney disease. There are many cysts in both kidneys. The cysts will grow up gradually. Most patients develop kidney disease after 20 years old. The volume of kidney increases significantly. In severe cases, kidney function is affected. Serum creatinine rises and eventually progresses to uremia.
In patients with polycystic kidney disease, urinary protein is still very low, even negative, even though renal function is decreased and serum creatinine is elevated.
In addition, urinary protein in patients with interstitial nephritis, gouty nephropathy and ischemic nephropathy is also very low. These six kinds of nephropathy, although the urinary protein is low, will still seriously threaten the kidney function, can not be judged according to the urinary protein, in order to avoid delaying the disease due to the misleading of urinary protein.
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