What Should be Done If Steroid Therapy is Not Effective for Pediatric Nephrotic Syndrome
2024-03-20 17:30
This is a complex issue that requires specific analysis for each individual case.
Most cases of pediatric nephrotic syndrome are caused by minimal change disease, which is typically sensitive to steroids. However, some patients may develop steroid dependence or resistance. A significant number of these patients experience reduced steroid efficacy due to various factors, while only a small percentage have genetic problems. It is critical to identify and analyze these specific drug resistance genes in order to develop targeted treatments. If you have kidney problems, you can contact me at the following email or Whatsapp. I will advise you personally.
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Therefore, when we encounter children with steroid dependence or resistance, we must actively seek to identify the influencing factors. For example, we need to assess the child's thyroid function, check for edema, and see if there is mucosal edema in the gastrointestinal tract that could affect absorption. We also need to consider whether there are conditions such as hypoproteinemia or hyperlipidemia that may affect treatment outcomes. It is essential to address and eliminate these factors.
It is also important to monitor the patient for infections, especially appendicitis and cholecystitis. We must carefully detect and identify any hidden infections that may affect the effectiveness of treatment. It is essential not to jump to the conclusion that a patient is steroid dependent or resistant. After ruling out these factors, we recommend genetic testing to determine if there are any drug resistance genes and then proceed with specific treatment based on the individual situation.
Our hospital treats nephrotic syndrome with a combined approach of traditional Chinese medicine and Western medicine, with an emphasis on the external application of traditional Chinese medicine. We have seven unique traditional Chinese medicine treatment methods. Through methods such as tonifying the spleen and kidney, clearing heat and eliminating dampness, and promoting blood circulation to remove obstructions, combined with dietary adjustments and improvements in lifestyle habits, we can not only alleviate symptoms, but also effectively improve the overall kidney function, emphasizing the overall balance of the body. Compared with some Western medical treatments, traditional Chinese medicine often has fewer side effects, especially in alleviating clinical manifestations and reducing the side effects caused by steroid immunosuppressants.
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