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How to Diagnose Purpura Nephritis

2013-10-07 15:57

Purpura nephritis is induced by Henoch-Schonlein Purpura, and Necrotizing vasculitis is its major pathologic change. There are many clinical symptoms in purpura nephritis patients, and rash, edema, arthritis, stomachache and nephritis are the major. To diagnose Purpura Nephritis, there are a lot of tests that are needed.

Routine Blood test

With toutine blood test, we can know clearly about the serum creatinine level and blood urea nitrogen level. Creatinine level and urea nitrogen level increases when kidney function is impaired severely, therefore, routine blood test helps to reflect whether kidney function is affected.

Urine test

Blood urine, protein urine is the common symptoms that patients with Purpura Nephritis often have. Blood urine is mainly caused by nephritis, but some may be caused by the bleeding in the surface of urinary mucosa. Protein urine is mainly caused by kidney damages, and they can also leak from gastrointestinal tracts and subcutaneous tissues.

Kidney biopsy

Kidney biopsy is an effective manner to diagnose kidney disease. In the kidney biopsy for Purpura Nephritis, the proliferation of mesangial cell may be found, at the same time, endothelial cells and epithelial cells may also have proliferation. The proliferation of epithelial cells may lead to the formation of crescents, and the formation of crescents is thought to be the most obvious symptom.

Test for inducing allergens

Patients with purpura nephritis are caused by anaphylactoid purpura, which is caused by allergens. So, testing out the inducing allergens is important for avoiding being infected twice, which will aggravate patients’ condition.

In the end, there are many other tests for Purpura Nephritis. And due to the difference of illness condition, patients may need to take different tests (If you are interested in learning more details about these tests, please feel free to consult our on-line doctors). Besides, a timely diagnosis is the basic for one Purpura Nephritis patient to have a timely effectively. Therefore, if someone find he has Purpura Nephritis symptoms, going to hospital for tests as soon as possible is very necessary.

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